GIVING PCC (BERIPLEX) IN AN EMERGENCYExtract from The Pulse, 27th April 2023 Intracranial Haemorrhage -Any delays in administration of PCC, particularly in intracranial haemorrhage (ICH) can lead to patient death or serious morbidity-Where intracranial haemorrhage is suspected or confirmed in a patient on anticoagulants, PCC should be given within 1 hour-In patients with rapid onset neurological signs while on warfarin perform an URGENT INR and CT scan (within 1 hour)Major Haemorrhage In the event of a major bleed, reverse anticoagulants within 1 hourRemember: -Order PCC straight from the Transfusion Laboratory-PCC does not require Haematology Consultant approval-Give vitamin K when reversing warfarin with PCCFor more information please refer toAlgorithm for management of bleeding and excessive anticoagulation in adult patients on warfarin in adults: https://twhqpulse02.mtw.nhs.uk/QPulseDocumentServiceOrgWideDocumentation/Documents.svc/documents/active/attachment?number=RWF-OWP-APP212Algorithm for management of bleeding on direct oral anticoagulant (DOACs) in adults: https://twhqpulse02.mtw.nhs.uk/QPulseDocumentServiceOrgWideDocumentation/Documents.svc/documents/active/attachment?number=RWF-OWP-APP209The Transfusion Hub page on the intranet contains key information about Blood Transfusion at MTW – please take a look: Transfusion Hub | Intranet (mtw.nhs.uk)
Extract from The Pulse, 27th April 2023 Intracranial Haemorrhage -Any delays in administration of PCC, particularly in intracranial haemorrhage (ICH) can lead to patient death or serious morbidity-Where intracranial haemorrhage is suspected or confirmed in a patient on anticoagulants, PCC should be given within 1 hour-In patients with rapid onset neurological signs while on warfarin perform an URGENT INR and CT scan (within 1 hour)Major Haemorrhage In the event of a major bleed, reverse anticoagulants within 1 hourRemember: -Order PCC straight from the Transfusion Laboratory-PCC does not require Haematology Consultant approval-Give vitamin K when reversing warfarin with PCCFor more information please refer toAlgorithm for management of bleeding and excessive anticoagulation in adult patients on warfarin in adults: https://twhqpulse02.mtw.nhs.uk/QPulseDocumentServiceOrgWideDocumentation/Documents.svc/documents/active/attachment?number=RWF-OWP-APP212Algorithm for management of bleeding on direct oral anticoagulant (DOACs) in adults: https://twhqpulse02.mtw.nhs.uk/QPulseDocumentServiceOrgWideDocumentation/Documents.svc/documents/active/attachment?number=RWF-OWP-APP209The Transfusion Hub page on the intranet contains key information about Blood Transfusion at MTW – please take a look: Transfusion Hub | Intranet (mtw.nhs.uk)
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